Monday, April 29, 2013

Asbestos Breaks And Fragments Can Cause Mesothelioma Disease.


Exposure to asbestos can cause fatal diseases dangerous. When asbestos fibers are broken or crushed into small pieces, they can be inhaled or ingested, and attack the body. One interesting study is called, "genetic effects of crocidolite in Chinese hamster lung cells," Huang SL, D. Saggioro, H. Man and Michel HV Malling, Mutation Research / Fundamental and molecular mechanisms of mutagenesis, Volume 57, Number 2, 1978, pp. 225 -232. This excerpt: "Summary - cells Chinese hamster lung in the presence of crocidolite showed inhibition of cell growth, death of the cultured cells is directly related to phagocytosis than observed with trypan blue soluble components connected fibers apparently inhibits crocidolite cell growth chromosome aberration caused by asbestos is broken and fragments .... -. aberrations limited mainly to structural aberrations preparation for electron microscopy showed that the asbestos content in phagocytosed asbestos phagosomes rapidly appeared to be a weak mutagen in their ability to mutations in the gene locus increases hypoxanthine guanine. " .

Another interesting study is called, "the mortality of cohorts exposed to chrysotile asbestos" White, William MD - Journal of Occupational and Environmental Medicine: October 1977 - Volume 19 - Issue 11 Here is an excerpt: "Abstract - age cohort mortality 30,264 historic men was held from 1935 to 1945, while factory chrysotile products worked for a year or more and who were alive on January 1, 1945 observation. 94% complete., the whole course of the mortality ratio standardized (SMR) is only 0.61, while the SMR for all cancers was 0.75 for lung cancer, 0.93 and 1.05 for gastrointestinal cancer. Both men died from asbestosis. all SMR was higher for men who have five or more years than men who worked 1 -4 years of work, but the mortality rate in the 30 were the same after adjusting for age. diseases hours differences asbestos-related work has no effect on mortality., the data show a positive mortality experience of men exposed only to chrysotile. "



Another interesting study is called, "washing asbestos-related lung reflect the concentration of asbestos bodies" De Vuyst P, Dumortier P, E Moulin, N Yourassowsky, Roomans P, P Francquen and JC YERNAULT - Eur Respir J 1988 , 1: 362 -367. Here is an excerpt: "Asbestos body (AB) counts both bronchoalveolar lavage fluid (BAL) and lung tissue samples were digested in a hundred patients who underwent thoracotomy procedure, especially for lung cancer shows a good correlation. (P = 0.73) between the two sets of values ​​of the entire group of objects found., if taken into account when choosing a restrictive as washing ipsilateral easy to analyze, interpret qualified doctor adopted a better correlation ( R = 0.82). No. AB low sperm count or AB (AB least 1 / ml) BAL approximately 70% less than 1,000 AB / g concentrations and less than 100% 10 000 concentrations ab / g. Los BAL patients with more than one AB / ml 85% of lung tissue comprises more than 1000 AB / g tissue and contained more than 44% 10,000 b / g A 10 AB / ml of BAL, all contained in lung tissue over 10 000 AB / G With the lung tissue is not readily available for patients undergoing consideration by asbestos exposure, BAL analysis appears to be a useful tool for assessing the concentration of light AB. This technique can be done, but only in patients with severe respiratory failure that does not allow adequate recovery BAL ".

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